The CDC estimates that 19 drug-resistant pathogens cause 9.7 million infections and more than 50,000 deaths annually in the U.S., with resistance continuing to outpace development of new treatments. “The agency considers this problem to be one of our most urgent public health threats,” reports NBC News. From the report: The report is the CDC’s first comprehensive assessment of these drug-resistant pathogens in seven years. […] The new report offers a detailed picture of these threats in the U.S., including a ranking of which are the most urgent concerns, based on the number and severity of infections they cause and how easily preventable or transmissible they are. The ranking also factors in how many treatment options exist and their costs. […] The report estimates that 19 drug-resistant germs cause 9.7 million infections annually in the U.S. Of these, four pathogens are ranked as most worrisome, including the fungus Candida auris and the bacteria that causes gonorrhea, which has become resistant to all but one class of antibiotics used to treat it.

The other two urgent threats, according to the CDC, are the bacteria Acinetobacter and Enterobacterales, both of which are resistant to a class of antibiotics widely considered a “last resort” for patients. In addition, the report adds a new bacteria to the list of “concerning” threats, which are considered less worrisome but still warrant monitoring: neisseria meningitidis, which causes meningococcal disease. The rare but life-threatening illness can be prevented through childhood vaccinations, but the bacteria that causes it is slowly developing a resistance to penicillin and another antibiotic called ciprofloxacin.

The report also offers some good news: The CDC determined that the bacteria Clostridioides difficile, or “C. diff,” which causes diarrhea and inflammation of the colon and can be deadly, is causing fewer cases year over year. The agency downgraded it to a serious threat, whereas it was categorized as urgent in the prior version of the report, which came out in 2019.

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You can probably still read on it, and, with some finessing, you can turn it into a useful display.

The Slate Truck is known for offering hundreds of customization options, but one common truck option isn’t available (yet.)

iOS 27.2 comes with some changes for Apple CarPlay, too.

An anonymous reader quotes a report from CBS News: Greenhouse gas concentrations in the atmosphere rose to record highs in 2025, locking in climate impacts that will persist for centuries, the United Nations said on Tuesday. Levels of the three main greenhouse gases — the climate-warming carbon dioxide, methane and nitrous oxide — all rose to unprecedented figures in 2025, the U.N.’s weather and climate agency said. The World Meteorological Organization said the rise would lead to more long-term temperature increases for the planet.

The bulletin looks at greenhouse gas concentrations — the amount of those gases in the atmosphere — rather than new annual emissions amounts as the world burns more coal, oil and gas. In 2025, carbon dioxide concentrations were at 426.8 parts per million (ppm); methane at 1,948 parts per billion, and nitrous oxide at 339.1 parts per billion. That takes them, respectively, to 153%, 267% and 126% of the pre-industrial levels witnessed before 1750. Of the three major greenhouse gases, CO2 accounts for about 66% of the warming effect on the climate.

Around half of the total CO2 emitted each year remains in the atmosphere; the rest is absorbed by the land and oceans. From 2024 to 2025, the global average concentration of CO2 rose by 2.8 ppm — smaller than the record surge from 2023 to 2024 of 3.6 ppm. WMO senior scientific officer Oksana Tarasova said this reflected the “recovery of the land carbon sinks and reduced fire carbon emissions in 2025 after the strong 2023/2024 El Nino,” the naturally occurring, climate-warming weather phenomenon. “However, a 2.8 ppm annual increase is still a substantial addition of carbon to the atmosphere from fossil fuel burning.” It is also above the average growth rate for the past decade of 2.6 ppm — a figure that stood at 0.8 ppm in the 1960s. “Another year, another new record,” said WMO Deputy Secretary-General Ko Barrett. “Greenhouse gases are trapping an unprecedented amount of heat in the atmosphere, providing energy for more extreme weather and associated risks to our economies and societies.

Further reading: UN Says Breaching 1.5C Warming Limit Is ‘Imminent and Unavoidable’

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Ford’s upcoming $28,350 Fathom electric truck will include a built-in inverter capable of supplying up to 10 kW of AC power to a home, bringing bidirectional charging to a significantly cheaper EV. Owners will still need additional Ford home hardware for features like outage backup and peak-rate energy management, but the company expects the necessary equipment to cost substantially less than its previous-generation system. CNET reports: The upcoming Fathom will be based on what Ford calls its Universal EV Platform, designed with the aid of its 2023 acquisition, startup Auto Motive Power, with bidirectional power on the plate from the start. The hardware required to invert the battery’s DC energy to an estimated 10 kW of AC home power will be built into the truck, so it won’t require a separate wall-mounted inverter box. Ford says the Fathom’s system will meet all applicable UL 1741 requirements and IEEE 1547 standards to ensure the vehicle is safely connected to the grid. As for the actual hardware you plug into your car, all signs point to the Fathom using the NACS plug type pioneered by Tesla and now widely adopted by new EVs in North America. In terms of the communication standard — the one that governs how AC power is routed from the slim wall box to the car’s onboard charger — that’ll be via SAE J3068, a software protocol developed for high-power, heavy-duty AC charging.

[…] However, while Fathom’s Universal EV Platform eliminates the need for a wall inverter box, it doesn’t completely bypass the need for additional hardware to make your home ready to accept bidirectional power. Say you wanted to take advantage of the Home Power Management feature to draw energy into the Fathom’s battery when power is cheapest, and then use that energy to offset peak-hour usage when power is most expensive. You’ll have to install at least the Ford Home Power Station in your home, at an additional cost. The automaker hasn’t specified pricing, but says that it’s working to reduce costs and expects this component alone to cost half as much as the first-generation Ford Home Energy system, which debuted at around $1,300. That could put the new system at roughly $650.

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Tailor your tech to fit your daily drive seamlessly.

The platform’s Discoverable Servers are about to get a lot more discoverable.

A Delaware proposal to let companies be operated by AI agents would help the firms’ human owners evade legal responsibility for reckless and harmful actions taken by the AI, US Rep. James Comer (R-Ky.) told Delaware Governor Matt Meyer in a letter yesterday.

Comer, chairman of the House Committee on Oversight and Government Reform, told Meyer that the committee “seeks assistance obtaining documents related to your state administration’s efforts to establish a new form of corporate entity to be known as an Artificial Intelligence Company (AIC).”

Comer said the proposal is ripe for abuse. “We are concerned that Delaware’s AIC proposal could be used to protect powerful AI companies and their investors from responsibility for reckless harmful actions, while also protecting non-transparent forces seeking anticompetitive regulatory capture behind state AI initiatives,” Comer’s letter said.

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The Securities and Exchange Commission‘s publication on Monday of Anthropic’s S-1 form—ahead of a heavily anticipated initial public offering—has led to plenty of discussion of whether the company’s quickly ballooning revenues will be able to overcome its even higher costs. But amid the numbers and forward-looking optimism about AI “rapidly transform[ing] every sector of the global economy in ways greater than the impact of industrialization, electricity, semiconductors, and the internet,” Anthropic also spends an inordinate amount of time in its S-1 laying out the myriad risk factors that could bring the company down.

Across 93 pages and over 70,000 words, Anthropic’s S-1 “Risk Factors” section discusses literally hundreds of potential problems that could negatively impact its business in the coming years. Many of these potential risks are the kind of standard worries about competition, costs, customer acquisition, and potential regulation that almost any business must worry about. But some risks highlight interesting potential points of failure for Anthropic specifically and the hype-filled AI bubble more generally.

After wading through Anthropic’s book-length treatise on its greatest risks, we’ve narrowed the list to the seven most surprising, interesting, or thought-provoking potential problems. Consider this a far-from-comprehensive look that potential Anthropic investors should keep in mind.

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It’s not an honest mistake; it’s the start of an attack on your wallet.

Intel, Oracle, IBM and IonQ have joined a growing list of companies objecting to having tokenized versions of their shares traded through OKX and Intercontinental Exchange’s blockchain venture, bringing the total number of objections to 26. About 37% of the companies on OKXICE’s original list have now opted out, according to CoinDesk. From the report: The four companies were named in an updated public notice (PDF) dated Monday, Oct. 26, from OKXICE, the two firms’ joint venture. They join earlier objectors including Microsoft, Alphabet, Goldman Sachs, Cisco and Wells Fargo. The growing list underscores a hurdle for OKXICE and the SEC’s new framework for tokenized stock trading: building a market that issuers are willing to join. The agency’s five-year “Innovation Exemption” gives qualifying venues room to test round-the-clock blockchain-based trading of stocks, and it also gives public companies an option to block their shares from being offered.

OKXICE issued its initial public notice on Oct. 4, outlining plans to use Uniswap v4 liquidity pools on OKX’s XLayer blockchain, with transactions settled in stablecoins. The venue would use automated market makers — software that executes trades through pools of assets rather than matching buyers and sellers through a conventional order book. Under the framework, venues must notify issuers and give them 30 days to object before offering tokenized versions of their shares.

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Apple has announced refreshes for the iMac and the entry-level, 14-inch MacBook Pro. Both machines are getting the M6 chip, which was introduced in the Mac mini several weeks ago.

The M6 is split into two variants for the iMac. Picking the “M6 chip with two Thunderbolt ports” option gets you a 10-core CPU and a 10-core GPU, whereas picking “M6 chip with four Thunderbolt ports” gets you 12 cores for each, instead. The two-port variant maxes out at 24 GB of RAM and 1TB of storage, whereas the four-port one maxes out at 32GB of RAM and 2TB of storage.

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While it can be jarring to discover that your companion is using AI glasses, there are some steps you can take to recognize them ASAP.

Since measles was declared eliminated in the US in 2000, the country’s occasional cases have come mainly from international travelers—visitors from far-flung places where the virus still spreads freely — or unvaccinated US residents who return from abroad with a highly infectious souvenir. But as vaccination rates have slipped nationwide in recent years and outbreaks grow bigger and more frequent, domestic travel now poses a greater risk than international incursions.

In a study published this week in NEJM Evidence, Washington state health officials highlight that risk, detailing how an explosive outbreak in South Carolina reached their distant state through five distinct importation events over two weeks in January. In all, the introductions led to 26 cases among residents before officials stamped out the spread.

South Carolina’s measles outbreak began on October 2, 2025, and was declared over on April 26, 2026. Officials confirmed 997 cases in the state during the outbreak. At the time, it was the largest measles outbreak recorded since the virus was declared eliminated, but Pennsylvania’s ongoing outbreak has since surpassed it.

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