Instagram is rolling out an app update that is surprisingly robust, bringing a whole bunch of new features to content creators. First and foremost, there’s finally some new camera filters, which should shake things up for a while. These filters range from “subtle color edits” to more expressive and stylized options.

There are some other minor Camera Roll improvements to make it easier to find what you need as you edit. These include updated previews, a refined search function and even the ability to zoom.

As for video editing, there’s a new undo/redo tool that lets you, surprise, undo actions and redo them with the press of a button. Instagram also says it’s testing the ability to scale, crop and rotate individual clips as part of the editing process. The audio tools are also getting some love, as you can pull audio clips from a dedicated media hub to accompany a Reel. Followers can remix this content as they see it. If this sounds a lot like TikTok, well, that’s because it is.

To that end, there are 10 new English text-to-speech voices to choose from, though they are only available in select countries for now. Additionally, there are six new text fonts and styles available to caption up your Reels or Stories, in addition to bolded outlines that should really make your copy pop. Hopefully.

If you really want to make something weird, Instagram now allows you to pull any part of a photo or video and turn it into a custom sticker. This also works the other way around, so users can pull eligible content from a favorite creator and turn it into a sticker. This particular tool was aided in development by Meta’s custom Segment Anything AI.

Finally, there are some updated tools for creators to keep track of their slow and steady rise to viral fame. The Retention Chart will offer a moment-by-moment insight into how many people are watching your content, though it’s not rolling out for a couple of months. The rest of these tools are available today.

This article originally appeared on Engadget at https://www.engadget.com/instagram-update-adds-new-camera-filters-and-video-editing-tools-for-content-creators-171537564.html?src=rss

Source: Engadget – Instagram update adds new camera filters and video editing tools for content creators

In a trial run by Verve Therapeutics, a Cambridge–based biotech company, researchers discovered that a single infusion of a gene-editing treatment called VERVE-101 was able to reduce cholesterol levels in patients. This treatment was tested in individuals with hereditary conditions that made them susceptible to developing clogged arteries and heart attacks. Scientists were able to use CRISPR editing techniques to tweak liver gene cells. The researchers “turned off” a cholesterol-raising gene called PCSK9, which is found in the liver, in order to lower LDL-C — sometimes called “bad” cholesterol — which causes plaque to build up in arteries in the first place.

PCSK9 was lowered by as much as 84 percent in the cohorts that received higher infusion rates of the treatment. At those higher treatment doses, Verve scientists said that the reduction of those LDL-C-related proteins lasted 2.5 years in previous studies on primates.

From a clinical standpoint, this gene editing therapy has the potential to disrupt the current standard treatment for high cholesterol. The current go-to’s include prescription statins and PCSK9 inhibitors, but they require strict adherence and can have bad side effects like muscle pain and memory loss.

CRISPR, while seemingly miraculous, is a long way from replacing daily medications though. According to Nature, two of the 10 participants in the study suffered from a “cardiovascular event” that coincided with the infusion. Verve says one was not related to the treatment at all and the second was “potentially related to treatment due to proximity to dosing.” The use of a gene-editing technology will always carry some risk because the edits could occur elsewhere in the genome.

Before a single infusion therapy for high cholesterol can reach consumers, the FDA mandates that the treatment will need to be studied for up to 15 years. Verve recently received FDA clearance for an Investigational New Drug Application for VERVE-101, meaning that the company can begin to conduct trials in the US. The current trials in New Zealand and the United Kingdom will look for willing clinical trial participants to expand the study.

This article originally appeared on Engadget at https://www.engadget.com/researchers-developed-a-gene-editing-technology-that-reduces-bad-cholesterol-170040293.html?src=rss

Source: Engadget – Researchers developed a gene-editing technology that reduces ‘bad’ cholesterol

Tablets are always going to be popular items during Black Friday sales. They make for great gifts, and it’s as good a time as any to pick one up for yourself if you’ve been on the fence. Google’s Pixel Tablet is a solid choice, especially if you lean more toward Android than iOS (or iPadOS).

The 128GB version of the 11-inch Pixel Tablet has dropped back down to its all-time-low price of $399 at Amazon ahead of Black Friday. That’s $100 off the regular price. If you opt for the porcelain variant with 128GB of storage, you can get a case (which is normally $80) at no extra cost. Either way, the tablet comes with a charging dock. Meanwhile, the 256GB model is also $100 off at $499 — there’s no SD card slot to expand the storage, unfortunately.

We gave the Pixel Tablet a score of 85 in our review in June. Being able to plop the tablet onto the dock (which has a built-in speaker) is a big selling point as that effectively turns the tablet into a smart display. In this mode, you can use the tablet to stream music and video, control and monitor smart home devices, display your favorite photos and more. Thanks to Google Assistant, you’ll be able to do much of this hands free. That said, the dock perhaps doesn’t position the tablet at the most flattering angle for video calls. The case that you can get for free with the 128GB model handily has a kickstand.

The performance is fairly snappy thanks to the Tensor G2 chipset, while the 2,560 x 1,600 LCD display is decent enough (although being limited to a 60Hz refresh rate is a drag). You should get a full day of use out of the tablet before you need to recharge the 5,000mAh battery. Google is also promising OS updates through at least June 2026 and security updates for two years beyond that at minimum.

On the downside, the lack of a headphone jack is galling. During our review period, we ran into a few software hiccups while the tablet was in Hub Mode as well. Overall, the Pixel Tablet isn’t quite as compelling as the Samsung Galaxy Tab S9 series when it comes to our pick for the best Android tablet. However, it’s still a strong choice for a more budget-friendly Android tablet. It’s significantly less expensive than Samsung’s models, especially during this sale.

Your Black Friday Shopping Guide: See all of Yahoo’s Black Friday coverage, here. Follow Engadget for Black Friday tech deals. Learn about Black Friday trends on In The Know. Hear from Autoblog’s experts on the best Black Friday deals for your car, garage, and home, and find Black Friday sales to shop on AOL, handpicked just for you.

This article originally appeared on Engadget at https://www.engadget.com/googles-pixel-tablet-is-100-off-in-early-black-friday-sale-164321754.html?src=rss

Source: Engadget – Google’s Pixel Tablet is 0 off in early Black Friday sale