A newly FDA-approved form of adaptive deep-brain stimulation (DBS) for Parkinson’s disease adjusts electrical stimulation in real time based on an individual’s brain signals, improving symptom control and reducing medication dependence. Scientific American: For decades, Keith Krehbiel took high doses of medications with a debilitating side effect — severe nausea — following his diagnosis with early-onset Parkinson’s disease at age 42 in 1997. When each dose wore off, he experienced dyskinesia — involuntary, repetitive muscle movements. In his case, this consisted of head bobbing and weaving. Krehbiel is among one million Americans who live with this progressive neurological disorder, which causes slowed movements, tremors and balance problems. But soon after surgery to implant electrodes into specific areas of his brain in 2020, his life dramatically improved. “My tremor went away almost entirely,” says Krehbiel, now age 70 and a professor emeritus of political science at the Stanford Graduate School of Business, whose Parkinson’s symptoms began at age 40 and were initially misdiagnosed as repetitive stress injury from computer use. “I reduced my Parkinson’s meds by more than two thirds,” he adds. “And I no longer have a sensation of a foggy brain, nor nausea or dyskinesia.”

Krehbiel was the first participant to enroll in a clinical trial testing a new form of deep-brain stimulation (DBS), a technology that gained approval from the U.S. Food and Drug Administration for Parkinson’s tremor and essential tremor in 1997 (it was later approved for other symptoms and conditions). The new adaptive system adjusts stimulation levels automatically based on the person’s individual brain signals. In late February it received FDA approval for Parkinson’s disease “based on results of the international multicenter trial, which involved participants at 10 sites across a total of four countries — the U.S., the Netherlands, Canada and France. This technology is suitable for anyone with Parkinson’s, not just individuals in clinical trials, says Helen Bronte-Stewart, the recent trial’s global lead investigator and a neurologist specializing in movement disorders at Stanford Medicine. “Like a cardiac pacemaker that responds to the rhythms of the heart, adaptive deep-brain stimulation uses a person’s individual brain signals to control the electric pulses it delivers,” Bronte-Stewart says. “This makes it more personalized, precise and efficient than older DBS methods.”

“Traditional DBS delivers constant stimulation, which doesn’t always match the fluctuating symptoms of Parkinson’s disease,” adds neurologist Todd Herrington, another of the trial’s investigators and director of the deep-brain stimulation program at Massachusetts General Hospital. With adaptive DBS, “the goal is to adjust stimulation in real time to provide more effective symptom control, fewer side effects and improved patient quality of life.” Current FDA approval of this adaptive system is for the treatment of Parkinson’s only, not essential tremor, dystonia (a neurological disorder that causes excessive, repetitive and involuntary muscle contractions) or epilepsy, which still rely on traditional, continuous DBS, Herrington says.

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An anonymous reader quotes a report from Variety: More than 400 Hollywood creative leaders signed an open letter to the Trump White House’s Office of Science and Technology Policy, urging the administration to not roll back copyright protections at the behest of AI companies. The filmmakers, writers, actors, musicians and others — which included Ben Stiller, Mark Ruffalo, Cynthia Erivo, Cate Blanchett, Cord Jefferson, Paul McCartney, Ron Howard and Taika Waititi — were submitting comments for the Trump administration’s U.S. AI Action Plan. The letter specifically was penned in response to recent submissions to the Office of Science and Technology Policy from OpenAI and Google, which asserted that U.S. copyright law allows (or should allow) allow AI companies to train their system on copyrighted works without obtaining permission from (or compensating) rights holders.

“We firmly believe that America’s global AI leadership must not come at the expense of our essential creative industries,” the letter says in part. The letter claims that “AI companies are asking to undermine this economic and cultural strength by weakening copyright protections for the films, television series, artworks, writing, music and voices used to train AI models at the core of multibillion-dollar corporate valuations.” […] The letter says Google and OpenAI “are arguing for a special government exemption so they can freely exploit America’s creative and knowledge industries, despite their substantial revenues and available funds. There is no reason to weaken or eliminate the copyright protections that have helped America flourish.” You can read the full statement and list of signatories here.

The letter was issued in response to recent submissions from OpenAI (PDF) and Google (PDF) claiming that U.S. law allows, or should allow, AI companies to train their programs on copyrighted works under the fair use legal doctrine.

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fahrbot-bot shares a report from Reuters: BYD on Monday unveiled a new platform for electric vehicles (EVs) that it said could charge EVs as quickly as it takes to pump gas and announced for the first time that it would build a charging network across China. The so-called “super e-platform” will be capable of peak charging speeds of 1,000 kilowatts (kW), enabling cars that use it to travel 400 km (249 miles) on a 5-minute charge, founder Wang Chuanfu said at an event livestreamed from the company’s Shenzhen headquarters.

Charging speeds of 1,000 kW would be twice as fast as Tesla’s superchargers whose latest version offers up to 500 kw charging speeds. The new charging architecture will be initially available in two new EVs — Han L sedan and Tang L SUV priced from 270,000 yuan ($37,328.91) and BYD said it would build over 4,000 ultra-fast charging piles, or units, across China to match the new platform. “In order to completely solve our user’s charging anxiety, we have been pursuing a goal to make the charging time of electric vehicles as short as the refuelling time of petrol vehicles,” Wang said.

“This is the first time in the industry that the unit of megawatt (charge) has been achieved on charging power,” he said.

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According to The Verge, legacy G Suite accounts will soon lose their individual storage allotment perks and be transitioned to pooled storage, which will be “shared across all users within your organization.” The changes will come into effect starting May 1st. From the report: G Suite was rebranded as Workspace in 2020. G Suite legacy free edition, which Google stopped offering in 2012, provides each user with 15GB of free allocated storage and was offered for personal use — making it ideal for families or groups that need to share a collective domain. Existing users have been permitted to access Workspace services at no additional charge, but Google says it’s now making this change because pooled storage provides a “simpler and more flexible way to manage storage.” “Google Workspace customers have had the benefit of pooled storage for years, and now we’re rolling it out to users with this legacy offering,” Google spokesperson Jenny Thomson told The Verge.

No action is required for the switch according to Google, and users cannot opt out of the pooled storage transition. The total amount of storage allocated to the entire G Suite account won’t be reduced, but if more storage is required then it can be purchased “at a discount” starting at increments of 100GB, which typically costs $15. Google hasn’t specified how large this discount will be. Storage limitations can still be set for each user within the G Suite account after the transition to prevent the collective storage pool from being hogged by individual users. These limits will have to be manually assigned by an account admin, however.

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With the release of The Day the Earth Blew Up, you’d think Warner Bros. would celebrate one of its most iconic franchises.

Roku is testing autoplaying video ads that play before users can access the home screen. While Roku claims this is just an experiment, users are threatening to abandon the platform if the change becomes permanent. Ars Technica reports: Reports of Roku customers seeing video ads automatically play before they could view the OS’ home screen started appearing online this week. A Reddit user, for example, posted yesterday: “I just turned on my Roku and got an unskippable ad for a movie, before I got to the regular Roku home screen.” Multiple apparent users reported seeing an ad for the movie Moana 2. When reached for comment, a Roku spokesperson shared a company statement that confirms that the autoplaying ads are expected behavior but not a permanent part of Roku OS currently. Instead, Roku claimed, it was just trying the ad capability out.

Roku’s representative said that Roku’s business “has and will always require continuous testing and innovation across design, navigation, content, and our first-rate advertising products,” adding: “Our recent test is just the latest example, as we explore new ways to showcase brands and programming while still providing a delightful and simple user experience.”

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Travel deals can be hit or miss as prices jump around and deals disappear before you can check your schedule. The OneAir Elite Lifetime Subscription is designed to do the heavy lifting for you. A members-only deal-alert service, it tracks flight prices using AI, scans for mistake fares, and alerts you when there’s a significant drop—and currently, it’s on StackSocial for $99.99 (originally $790), but apply the promo code FLY30 and you can get it for just $70. The sale runs until March 30.

OneAir’s coverage is broad, spanning 60+ countries and multiple fare classes, including premium economy and business. That’s useful if you’re flexible with your routes and don’t mind hopping on an unexpected deal. It even includes hidden city fares, which can sometimes cut costs significantly. The biggest advantage here is that OneAir does the searching for you, so that you’re not spending hours checking flights manually. However, travelers with strict schedules or those who only fly specific airlines may not always get the most value. Some of the best deals require booking fast, so it works best for those ready to jump on an opportunity.

At $70 for lifetime access, it’s cheaper than most annual flight deal subscriptions, and if you book even one discounted flight using its alerts, it could pay for itself in one trip. That said, it won’t magically make every flight cheaper—deals depend on availability and timing. If you like tracking flights yourself or only travel occasionally, free services like Google Flights or Skyscanner alerts might be enough. But if you want to save money without the hassle, this could be a solid tool to have.

An anonymous reader quotes a report from Politico: A top Commerce Department official sent a blistering email to his former colleagues on his way out the door Sunday warning that the Trump administration is poised to unduly enrich Elon Musk’s satellite internet company with money for rural broadband. The technology offered by Starlink … is inferior, wrote Evan Feinman, who had directed the $42.5 billion broadband program for the past three years. “Stranding all or part of rural America with worse internet so that we can make the world’s richest man even richer is yet another in a long line of betrayals by Washington,” Feinman said.

Feinman’s lengthy email, totaling more than 1,100 words and shared with POLITICO, is a sign of deep discomfort about the changes underway that will likely transform the Broadband Equity, Access and Deployment Program. Commerce Secretary Howard Lutnick recently pledged a vigorous review of BEAD, with an aim to rip out what he sees as extraneous requirements and remove any preference for particular broadband technologies like fiber. The program, created in the 2021 infrastructure law program, became a source of partisan fighting last year on the campaign trail as Republicans attacked the Biden administration for its slow pace. No internet expansion projects have begun using BEAD money, although some states were close at the beginning of this year. Feinman’s critique: In his email, Feinman notes Friday was his last day leading BEAD and that he’s “disappointed not to be able to see this project through.”

Feinman’s email warns the Trump administration could undermine BEAD and he encourages people to fight to retain its best aspects. Feinman said the administration should “NOT change it to benefit technology that delivers slower speeds at higher costs to the household paying the bill,” adding that this isn’t what rural America, congressional Republicans or Democrats, the states or the telecom industry wants. “Reach out to your congressional delegation and reach out to the Trump Administration and tell them to strip out the needless requirements, but not to strip away from states the flexibility to get the best connections for their people,” Feinman wrote. He said he’s not worried about the Trump administration nixing requirements around climate resiliency, labor and middle class affordability, saying those issues “were inserted by the prior administration for messaging/political purposes, and were never central to the mission of the program.” Feinman warns that changes to the BEAD program under the Trump administration could stall state-level broadband progress, with Louisiana, Delaware, and Nevada already stuck in review.

Meanwhile, no specific guidance or timeline for these changes has been provided, and Arielle Roth’s confirmation as NTIA head is still pending in the Senate.

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