Previous Radeon generations supported up to 4-way CrossFire configurations, but no more: AMD confirmed that RX Vega will top out at 2-way configurations — at least in games. “We have delivered two-way mGPU support in games,” an AMD representative told PCWorld via email. “Three- and four-way configurations will continue being supported in compute and professional applications.”
AMD’s move isn’t unprecedented. NVIDIA nerfed SLI (its brand name for multi-GPU support) with the launch of its current-generation graphics cards, the GTX 10-series, which also tops out at 2-way support in traditional games. Like AMD, NVIDIA killed support for these extreme enthusiast setups quietly, only fessing up to the change when asked for comment by the press.
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Source: [H]ardOCP – Radeon RX Vega Won’t Get 4-Way Multi-GPU Support in Games