{"id":1238158,"date":"2025-03-09T13:34:00","date_gmt":"2025-03-09T17:34:00","guid":{"rendered":"https:\/\/www.prime-wow.com\/?p=1238158"},"modified":"2025-03-09T13:34:00","modified_gmt":"2025-03-09T17:34:00","slug":"stem-cell-therapy-trial-reverses-irreversible-damage-to-cornea","status":"publish","type":"post","link":"https:\/\/www.prime-wow.com\/?p=1238158","title":{"rendered":"Stem Cell Therapy Trial Reverses &#8216;Irreversible&#8217; Damage to Cornea"},"content":{"rendered":"<div>Damaged corneas were repaired at a Harvard teaching hospital in a unique clinical trial, reports New Atlas:<\/p>\n<p>Since it&#8217;s on the frontline of potential hazards from the outside world, the cornea features a population of limbal epithelial stem cells, which repair minor damage to keep the surface smooth and functional&#8230; The new study, conducted by scientists at Massachusetts Eye and Ear, investigated a new treatment called cultivated autologous limbal epithelial cells (CALEC). This involves removing stem cells from a patient&#8217;s uninjured eye, growing their population in the lab for a few weeks, then surgically transplanting them into the injured eye.<br \/>\nThe phase 1\/2 trial recruited 14 patients to undergo the procedure, and followed them for 18 months afterwards&#8230; By the first checkup at three months, the corneas of seven (50%) of the participants had been completely restored. By the 12-month mark, that number had increased to 11 (79%) patients. Two other participants met the definition for partial success, so the team claims an overall success rate of 92% for CALEC.<\/p>\n<div class=\"share_submission\" style=\"position:relative;\">\n<a class=\"slashpop\" href=\"http:\/\/twitter.com\/home?status=Stem+Cell+Therapy+Trial+Reverses+'Irreversible'+Damage+to+Cornea%3A+https%3A%2F%2Fscience.slashdot.org%2Fstory%2F25%2F03%2F09%2F1612213%2F%3Futm_source%3Dtwitter%26utm_medium%3Dtwitter\"><img decoding=\"async\" src=\"https:\/\/www.prime-wow.com\/wp-content\/uploads\/2025\/03\/twitter_icon_large-141.png\"><\/a><br \/>\n<a class=\"slashpop\" href=\"http:\/\/www.facebook.com\/sharer.php?u=https%3A%2F%2Fscience.slashdot.org%2Fstory%2F25%2F03%2F09%2F1612213%2Fstem-cell-therapy-trial-reverses-irreversible-damage-to-cornea%3Futm_source%3Dslashdot%26utm_medium%3Dfacebook\"><img decoding=\"async\" src=\"https:\/\/www.prime-wow.com\/wp-content\/uploads\/2025\/03\/facebook_icon_large-143.png\"><\/a><\/p>\n<\/div>\n<p><a href=\"https:\/\/science.slashdot.org\/story\/25\/03\/09\/1612213\/stem-cell-therapy-trial-reverses-irreversible-damage-to-cornea?utm_source=rss1.0moreanon&amp;utm_medium=feed\">Read more of this story<\/a> at Slashdot.<\/p>\n<p><iframe src=\"https:\/\/slashdot.org\/slashdot-it.pl?op=discuss&amp;id=23630985&amp;smallembed=1\" style=\"height: 300px; width: 100%; border: none;\"><\/iframe><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Damaged corneas were repaired at a Harvard teaching hospital in a unique clinical trial, reports New Atlas: Since it&#8217;s on the frontline of potential hazards from the outside world, the cornea features a population of limbal epithelial stem cells, which &hellip; <a href=\"https:\/\/www.prime-wow.com\/?p=1238158\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[101,44,110],"tags":[],"class_list":["post-1238158","post","type-post","status-publish","format-standard","hentry","category-slashdot","category-technology","category-unfiltered-rss"],"_links":{"self":[{"href":"https:\/\/www.prime-wow.com\/index.php?rest_route=\/wp\/v2\/posts\/1238158","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.prime-wow.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.prime-wow.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.prime-wow.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.prime-wow.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1238158"}],"version-history":[{"count":0,"href":"https:\/\/www.prime-wow.com\/index.php?rest_route=\/wp\/v2\/posts\/1238158\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.prime-wow.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1238158"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.prime-wow.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1238158"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.prime-wow.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1238158"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}