{"id":1011182,"date":"2022-05-12T06:00:00","date_gmt":"2022-05-12T10:00:00","guid":{"rendered":"https:\/\/www.prime-wow.com\/?p=1011182"},"modified":"2022-05-12T06:00:00","modified_gmt":"2022-05-12T10:00:00","slug":"blocking-inflammation-may-lead-to-chronic-pain","status":"publish","type":"post","link":"https:\/\/www.prime-wow.com\/?p=1011182","title":{"rendered":"Blocking Inflammation May Lead To Chronic Pain"},"content":{"rendered":"<p>Using anti-inflammatory drugs and steroids to relieve pain could increase the chances of developing chronic pain, according to researchers from McGill University and colleagues in Italy. Neuroscience News reports: Their research puts into question conventional practices used to alleviate pain. Normal recovery from a painful injury involves inflammation and blocking that inflammation with drugs could lead to harder-to-treat pain. [&#8230;] In the study published in Science Translational Medicine, the researchers examined the mechanisms of pain in both humans and mice. They found that neutrophils &#8212; a type of white blood cell that helps the body fight infection &#8212; play a key role in resolving pain. Experimentally blocking neutrophils in mice prolonged the pain up to ten times the normal duration. Treating the pain with anti-inflammatory drugs and steroids like dexamethasone and diclofenac also produced the same result, although they were effective against pain early on.<\/p>\n<p>These findings are also supported by a separate analysis of 500,000 people in the United Kingdom that showed that those taking anti-inflammatory drugs to treat their pain were more likely to have pain two to ten years later, an effect not seen in people taking acetaminophen or anti-depressants. &#8220;Our findings suggest it may be time to reconsider the way we treat acute pain. Luckily pain can be killed in other ways that don&#8217;t involve interfering with inflammation,&#8221; says Massimo Allegri, a Physician at the Policlinico of Monza Hospital in Italy and Ensemble Hospitalier de la Cote in Switzerland.<\/p>\n<p \/>\n<div class=\"share_submission\">\n<a class=\"slashpop\" href=\"http:\/\/twitter.com\/home?status=Blocking+Inflammation+May+Lead+To+Chronic+Pain%3A+https%3A%2F%2Fbit.ly%2F3L1PlPL\"><img decoding=\"async\" src=\"https:\/\/www.prime-wow.com\/wp-content\/uploads\/2022\/05\/twitter_icon_large-452.png\" \/><\/a><br \/>\n<a class=\"slashpop\" href=\"http:\/\/www.facebook.com\/sharer.php?u=https%3A%2F%2Fscience.slashdot.org%2Fstory%2F22%2F05%2F12%2F018200%2Fblocking-inflammation-may-lead-to-chronic-pain%3Futm_source%3Dslashdot%26utm_medium%3Dfacebook\"><img decoding=\"async\" src=\"https:\/\/www.prime-wow.com\/wp-content\/uploads\/2022\/05\/facebook_icon_large-226.png\" \/><\/a><\/p>\n<\/div>\n<p><a href=\"https:\/\/science.slashdot.org\/story\/22\/05\/12\/018200\/blocking-inflammation-may-lead-to-chronic-pain?utm_source=rss1.0moreanon&amp;utm_medium=feed\">Read more of this story<\/a> at Slashdot.<\/p>\n<p>&#013;<br \/>\n&#013;<br \/>\nSource: Slashdot &#8211; <a href=\"https:\/\/science.slashdot.org\/story\/22\/05\/12\/018200\/blocking-inflammation-may-lead-to-chronic-pain?utm_source=rss1.0mainlinkanon&amp;utm_medium=feed\" target=\"_blank\" rel=\"noopener\">Blocking Inflammation May Lead To Chronic Pain<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Using anti-inflammatory drugs and steroids to relieve pain could increase the chances of developing chronic pain, according to researchers from McGill University and colleagues in Italy. Neuroscience News reports: Their research puts into question conventional practices used to alleviate pain. &hellip; <a href=\"https:\/\/www.prime-wow.com\/?p=1011182\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":1011183,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[101,110],"tags":[100],"class_list":["post-1011182","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-slashdot","category-unfiltered-rss","tag-slashdot"],"_links":{"self":[{"href":"https:\/\/www.prime-wow.com\/index.php?rest_route=\/wp\/v2\/posts\/1011182","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.prime-wow.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.prime-wow.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.prime-wow.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.prime-wow.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1011182"}],"version-history":[{"count":0,"href":"https:\/\/www.prime-wow.com\/index.php?rest_route=\/wp\/v2\/posts\/1011182\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.prime-wow.com\/index.php?rest_route=\/wp\/v2\/media\/1011183"}],"wp:attachment":[{"href":"https:\/\/www.prime-wow.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1011182"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.prime-wow.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1011182"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.prime-wow.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1011182"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}